Author

C. R. Harding

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. D. Uboldi· 1 shared A. J. Guerra· 1 shared A. L. Scott· 1 shared C. J. Tonkin· 1 shared D. Aghabi· 1 shared E. S. dos Santos Martins Duarte· 1 shared J. G. Wideman· 1 shared J. Ovciarikova· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperCell Biology

A. D. Uboldi

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3 papers

Recent·Most cited

Keeping FIT: Iron-mediated post-transcriptional regulation in Toxoplasma gondii

M. A. Sloan, A. L. Scott, C. R. Harding

The paper identifies iron-mediated post-transcriptional regulation in Toxoplasma gondii by showing that a stem-loop structure in the 3' UTR of a gene stabilizes its transcript and protein under low iron conditions.

bioRxiv · Nov 8, 2023 · PreprintMicrobiology

The vacuolar iron transporter mediates iron detoxification in Toxoplasma gondii

D. Aghabi, M. Sloan, Z. Dou, A. J. Guerra, C. R. Harding

This study identifies the vacuolar iron transporter (VIT) in Toxoplasma gondii as essential for iron detoxification, showing its role in managing iron levels and parasite survival.

bioRxiv · Sep 8, 2021 · PreprintCell Biology

Depletion of voltage-dependent anion channel (VDAC) of Toxoplasma gondii affects multiple mitochondrial functions, but not calcium signalling.

N. Mallo, E. S. dos Santos Martins Duarte, S. C. Baehr, M. Biddau, J. Ovciarikova, M.-L. Wilde, A. D. Uboldi, L. Lemgruber, C. J. Tonkin, J. G. Wideman, C. R. Harding, L. Sheiner

This study shows that VDAC in Toxoplasma gondii is essential for mitochondrial protein import and metabolite transfer but does not regulate calcium signaling.

bioRxiv · Oct 7, 2020 · PreprintCell Biology