Modeling clonal evolution and oncogenic dependency in vivo in the context of hematopoietic transformation
R. L. Bowman, A. Dunbar, T. Mishra, W. Xiao, M. R. Waarts, I. Fernandez Maestre, S. E. Eisman, L. Cai, S. F. Cai, P. Sanchez Vela, S. Mowla, A. R. Martinez Benitez, Y. Park, I. S. Csete, A. Krishnan, , R. L. Levine
This study models clonal evolution and oncogenic dependency in hematopoietic transformation using reversible mutagenesis and allelic frameworks.
bioRxiv · May 18, 2022 · PreprintCancer Biology