LUXendins reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics
J. Ast, A. Arvaniti, N. H. F. Fine, D. Nasteska, F. B. Ashford, Z. Stamataki, Z. Koszegi, A. Bacon, S. Trapp, B. J. Jones, B. Hastoy, A. Tomas, C. Reissaus, A. K. Linnemann, E. D'Este, , D. J. Hodson
The paper introduces LUXendin peptides that label and visualize endogenous GLP1R with high specificity, revealing receptor organization and dynamics.
bioRxiv · May 8, 2019Cell Biology