Author

B. Hastoy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Organism:human· 4 Approach:experimental assay· 3 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Assay:electrophysiology· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

S. Nawaz· 3 shared G. A. Rutter· 2 shared P. Marchetti· 2 shared A. Arvaniti· 1 shared A. Bacon· 1 shared A. Clark· 1 shared A. K. Linnemann· 1 shared A. Khamis· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersCell Biology

S. Nawaz

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Author profile →

4 papers

Recent·Most cited

Electrophysiological characterisation of iPSC-derived human β-like cells and an SLC30A8 disease model.

M. Jaffredo, N. A. J. Krentz, B. Champon, C. E. Duff, S. Nawaz, N. Beer, C. Honore, A. Clark, P. Rorsman, J. Lang, A. L. Gloyn, M. Raoux, B. Hastoy

This paper uses electrophysiological tools to functionally characterize iPSC-derived human β-like cells and assess the impact of a SLC30A8 variant on β-cell electrical coupling.

bioRxiv · Oct 17, 2023 · PreprintCell Biology

Roles for the long non-coding RNA Pax6os1/PAX6-AS1 in pancreatic beta cell identity and function.

L. Lopez-Noriega, R. M. Callingham, A. Martinez-sanchez, S. Nawaz, G. Pizza, N. Haberman, N. Cvetesic, M.-S. Nguyen-Tu, B. Lenhard, P. Marchetti, L. Piemonti, E. J. P. de Koning, A. M. J. Shapiro, P. R. Johnson, I. Leclerc, , G. A. Rutter

This study investigates the role of Pax6os1/PAX6-AS1 in beta cell identity and function, finding that its upregulation in diabetes contributes to impaired functionality and that targeting it may improve glucose homeostasis.

bioRxiv · Jul 17, 2020 · PreprintCell Biology

Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a new regulator of insulin secretion

M. Hu, I. Cebola, G. Carrat, S. Jiang, S. Nawaz, A. Khamis, M. Canouil, P. Froguel, A. Schulte, M. Solimena, M. Ibberson, P. Marchetti, F. L. Cardenas-Diaz, P. Gadue, B. HASTOY, , G. A. Rutter

The paper identifies FCHSD2 as a new regulator of insulin secretion by analyzing 3D chromatin interactions at the STARD10 locus in human islets.

bioRxiv · Mar 31, 2020Cell Biology

LUXendins reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics

J. Ast, A. Arvaniti, N. H. F. Fine, D. Nasteska, F. B. Ashford, Z. Stamataki, Z. Koszegi, A. Bacon, S. Trapp, B. J. Jones, B. Hastoy, A. Tomas, C. Reissaus, A. K. Linnemann, E. D'Este, , D. J. Hodson

The paper introduces LUXendin peptides that label and visualize endogenous GLP1R with high specificity, revealing receptor organization and dynamics.

bioRxiv · May 8, 2019Cell Biology