Author

A. K. Linnemann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cell Biology· 4

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Research Focus:cell type annotation· 4 Assay:imaging· 4 Approach:experimental assay· 3 Organism:human· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Approach:microscopy & imaging analysis· 2 Research Focus:clustering· 1

Frequent Co-Authors

A. M. Conteh· 2 shared C. Muralidharan· 2 shared J. J. Crowder· 2 shared M. M. Martinez· 2 shared A. Arvaniti· 1 shared A. Bacon· 1 shared A. N. Novak· 1 shared A. N. Twigg· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCell Biology

A. M. Conteh

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Author profile →

4 papers

Recent·Most cited

Real Time In vivo Analysis of Pancreatic Beta-cell Autophagic Flux Reveals Impairment Before Onset of Autoimmune Diabetes

O. Melnyk, C. Muralidharan, B. Duffett, A. N. Novak, G. Perez-Aviles, M. M. Martinez, J. J. Crowder, A. K. Linnemann

This study uses intravital microscopy to show autophagic flux defects in NOD mouse beta-cells before hyperglycemia onset, suggesting a causal role in T1D pathogenesis.

bioRxiv · May 23, 2023 · PreprintCell Biology

Pancreatic Beta Cell Autophagy is Impaired in Type 1 Diabetes

C. Muralidharan, A. M. Conteh, M. R. Marasco, J. J. Crowder, J. Kuipers, P. de Boer, B. N. G. Giepmans, A. K. Linnemann

This study shows impaired autophagy in pancreatic beta cells of type 1 diabetes patients and a mouse model, with reduced autophagosome-lysosome colocalization and telolysosome accumulation.

bioRxiv · Sep 10, 2020Cell Biology

LUXendins reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics

J. Ast, A. Arvaniti, N. H. F. Fine, D. Nasteska, F. B. Ashford, Z. Stamataki, Z. Koszegi, A. Bacon, S. Trapp, B. J. Jones, B. Hastoy, A. Tomas, C. Reissaus, A. K. Linnemann, E. D'Este, , D. J. Hodson

The paper introduces LUXendin peptides that label and visualize endogenous GLP1R with high specificity, revealing receptor organization and dynamics.

bioRxiv · May 8, 2019Cell Biology

Longitudinal Intravital Imaging of Biosensor-labeled In Situ Islet Beta Cells

C. A. Reissaus, A. N. Twigg, K. S. Orr, A. M. Conteh, M. M. Martinez, M. M. Kamocka, R. N. Day, S. A. Tersey, K. W. Dunn, R. G. Mirmira, A. K. Linnemann

This study uses intravital imaging of biosensor-labeled beta cells to monitor ROS dynamics in vivo during diabetes-related stress.

bioRxiv · Jan 14, 2019Cell Biology