C. S. Wright

Scaling of stochastic growth and division dynamics: A comparative study of individual rod-shaped cells in the Mother Machine and SChemostat platforms

The paper compares stochastic growth and division dynamics of bacterial cells in two microfluidic platforms, finding that mechanical confinement increases interdivision times but is compensated by division ratio adjustments.

Architectural underpinnings of stochastic intergenerational homeostasis

The paper identifies the core mechanism for stochastic intergenerational cell size homeostasis in bacteria using high-precision data and first passage process analysis.

Prrx1-driven LINC complex disruption in vivo reduces osteoid deposition but not bone quality after voluntary wheel running

This study shows that disrupting the LINC complex in bone progenitor cells reduces exercise-induced osteoid deposition but not bone quality in mice.

Non-Markovian memory in a bacterium

This study investigates whether bacterial cells retain memory of past environmental conditions across generations, finding non-Markovian memory in growth rates but not cell size.

Intergenerational scaling law determines the precision kinematics of stochastic individual-cell-size homeostasis

The paper develops a theoretical framework to explain intergenerational stochastic homeostasis in bacterial cell size, validated by experimental data from multiple microorganisms.

Emergent Simplicities in Stochastic Intergenerational Homeostasis

This paper identifies emergent simplicities in intergenerational homeostasis through experiments and theory, revealing a Markovian scaling law that determines stochastic homeostasis without fine-tuning parameters.

Deterministic Early Endosomal Maturations Emerge From a Stochastic Trigger-and-Convert Mechanism

The paper tracks endosomal maturation events using advanced imaging and simulations, revealing that maturation is driven by heterotypic EEA1-mediated interactions rather than autonomous stochastic processes.

Generation of two Multipotent Mesenchymal Progenitor Cell Lines Capable of Osteogenic, Mature Osteocyte, Adipogenic, and Chondrogenic Differentiation

The paper develops two mesenchymal progenitor cell lines that can differentiate into osteogenic, adipogenic, and chondrogenic lineages and mimic in vivo responses of key regulatory genes.