Author

C. Savage-Dunn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Physiology· 2

Signature Assays, Organisms & Methods

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Organism:C. elegans· 5 Approach:experimental assay· 5 Research Focus:development & morphogenesis· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:metabolism & bioenergetics· 2 Research Focus:cell type annotation· 1 Assay:electronic health records· 1

Frequent Co-Authors

E. J. Ciccarelli· 3 shared G. Ranepura· 2 shared M. Bendelstein· 2 shared A. Melendez· 1 shared A. Monas· 1 shared B. Dehapiot· 1 shared C. Cazevieille· 1 shared C. L. Essmann· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersPhysiology

E. J. Ciccarelli

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

TGF-β Ligand Cross-Subfamily Interactions in the Response of Caenorhabditis elegans to Bacterial Pathogens

E. J. Ciccarelli, Z. Wing, M. Bendelstein, R. K. Johal, G. Singh, A. Monas, C. Savage-Dunn

This study investigates TGF-β ligand interactions in C. elegans immune response, showing cooperative roles among ligands and distinct signaling pathway involvement.

bioRxiv · May 5, 2023Physiology

BMP signaling to pharyngeal muscle in the C. elegans response to a bacterial pathogen regulates anti-microbial peptide expression and pharyngeal pumping

E. J. Ciccarelli, M. Bendelstein, K. K. Yamamoto, H. Reich, C. Savage-Dunn

This study shows that BMP signaling in the pharynx of C. elegans coordinates anti-microbial peptide expression and pharyngeal pumping to enhance survival against bacterial pathogens.

bioRxiv · Mar 6, 2023Physiology

Meisosomes, folded membrane platforms, link the epidermis to the cuticle in C. elegans

D. Aggad, N. Brouilly, S. Omi, C. L. Essmann, B. Dehapiot, C. Savage-Dunn, F. Richard, C. Cazevieille, K. A. Politi, D. D. Hall, R. Pujol, N. Pujol

The paper identifies meisosomes in C. elegans as folded membrane structures linking the lateral epidermis to the cuticle, and shows their role in biomechanical integrity and damage response.

bioRxiv · Nov 26, 2021Cell Biology

Mechanism of Interaction of BMP and Insulin Signaling in C. elegans Development and Homeostasis

J. F. Clark, E. J. Ciccarelli, P. Kayastha, G. Ranepura, M. S. Hasan, A. Melendez, C. Savage-Dunn

This study identifies molecular interactions between BMP and IIS pathways in C. elegans, revealing three modes of interaction and their roles in lipid homeostasis and disease.

bioRxiv · Feb 10, 2021Cell Biology

C. elegans DBL-1/BMP Regulates Lipid Accumulation via Interaction with Insulin Signaling

J. Clark, M. Meade, G. Ranepura, D. H. Hall, C. Savage-Dunn

This study shows DBL-1/BMP signaling in C. elegans regulates lipid accumulation through interaction with insulin signaling, affecting lipid droplet size and count.

bioRxiv · Sep 19, 2017Cell Biology