Slow conduction and spatial dispersion of repolarization are intrinsic properties of cardiomyocyte electrophysiology that contribute to proarrhythmia in an iPSC model of hypertrophic cardiomyopathy
S. Lim, M. M. Mangala, M. Holliday, H. C. Szappanos, S. Barratt-Ross, W. Liang, G. Ranpura, J. I. Vandenberg, C. Semsarian, A. P. Hill, L. C. Hool
This study shows that HCM cardiomyocytes have slower conduction and increased repolarization dispersion, which contribute to arrhythmia in an iPSC model.
bioRxiv · Jul 20, 2023 · PreprintPhysiology