J.-F. Joanny

The Reissner fiber under tension in vivo shows dynamic interaction with ciliated cells contacting the cerebrospinal fluid

This study shows the Reissner fiber interacts dynamically with ciliated cells in zebrafish, affecting CSF flow and sensory function.

Cell adhesion and spreading on fluid membranes through microtubules-dependent mechanotransduction

The paper shows that cells spread on fluid lipid bilayers coated with Invasin, relying on microtubule-mediated forces rather than actomyosin contraction.

Volume regulation in adhered cells: roles of surface tension and cell swelling

The paper extends the pump-leak model to include mechano-sensitive ion transporters, explaining discrepancies in volume changes of adhered cells due to swelling and surface tension effects.

Cell size scaling laws: a unified theory

This paper presents a unified theory explaining cell size scaling laws through the Pump and Leak model, showing how physical constraints govern cellular dimensions and their breakdown in specific biological states.

Evolution of a confluent gut epithelium under cyclic stretching

This study examines how cyclic stretching affects intestinal epithelial cell orientation using Caco-2 cells on PDMS substrates, revealing a perpendicular alignment response and modeling it with a vertex model.

Crisscross multilayering of cell sheets

The paper shows that bilayering of myoblasts results from contractile active nematic organization and apical ECM secretion, leading to perpendicular cell layering.

A mechano-osmotic feedback couples cell volume to the rate of cell deformation

The paper shows that cell volume depends on the rate of deformation, proposing a mechano-osmotic coupling model involving actin cortex and ion fluxes.

Extra-cellular Matrix in cell aggregates is a proxy to mechanically control cell proliferation and motility

The paper shows that global compressions of cell aggregates affect growth and cell motility through residual mechanical stress on the extracellular matrix, while selective compressions do not.

A new actin depolymerase: a Myosin 1 motor

This study identifies myosin1b as a new actin depolymerase that enhances depolymerization at the barbed end through unique interactions, distinct from myosin II.

Actin shells control buckling and wrinkling of biomembranes

This study shows how varying actin shell thickness in reconstituted systems controls membrane shape changes under volume reduction, revealing a transition between buckling and wrinkling.

Active cargo positioning in antiparallel transport networks

The paper studies cargo positioning in antiparallel actin networks using colloidal beads and myosin motors, finding that beads accumulate at regions of neutral polarity with motor-dependent precision.

Extracellular Matrix acts as pressure detector in biological tissues

The paper shows that extracellular matrix detects mechanical compression in multicellular aggregates by regulating cell behavior through deformation and dehydration.

Macropinocytosis overcomes directional bias due to hydraulic resistance to enhance space exploration by dendritic cells

This study shows that macropinocytosis enables immature dendritic cells to overcome hydraulic resistance, enhancing their space exploration and tissue-patrolling function, while mature dendritic cells are hindered by this resistance.