F. Vacca

Human monoclonal antibodies reveal subdominant gonococcal and meningococcal cross-protective antigens

The paper identifies human monoclonal antibodies that recognize key antigens, PorB and LOS, providing cross-protection against gonococcal and meningococcal infections.

Functional characterization of Atlantic salmon (Salmo salar L.) PepT2 transporters

This study identifies and characterizes two PepT2 transporters in Atlantic salmon, showing they function as high-affinity/low-capacity peptide transporters with conserved amino acids and tissue-specific expression.

Extremely potent human monoclonal antibodies from convalescent Covid-19 patients

The paper isolates extremely potent human monoclonal antibodies from convalescent Covid-19 patients, effective against SARS-CoV-2 at low concentrations.

Identification of neutralizing human monoclonal antibodies from Italian Covid-19 convalescent patients

The paper isolates neutralizing human monoclonal antibodies from Covid-19 convalescent patients for therapeutic and prophylactic interventions.

A truncated form of HpARI stabilises IL-33, amplifying responses to the cytokine.

This study shows that a truncated form of HpARI stabilizes IL-33, enhancing immune responses to allergens and infections.

Drug-induced increase in lysobisphosphatidic acid reduces the cholesterol overload in Niemann-Pick type C cells and mice

The paper identifies thioperamide as a drug that increases lysobisphosphatidic acid (LBPA) levels, reducing cholesterol overload in Niemann-Pick type C cells and mice.

Cyclodextrin triggers MCOLN1-dependent endo-lysosome secretion in Niemann-Pick type C cells

This study shows cyclodextrin induces endo-lysosome secretion in Niemann-Pick type C cells via MCOLN1, reducing cholesterol storage.