Author

C. W. Euler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:clustering· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. Varble· 1 shared E. Campisi· 1 shared J. Bondy-Denomy· 1 shared J. Fyodorova· 1 shared J. Rostol· 1 shared J. W. Modell· 1 shared L. A. Marraffini· 1 shared M. J. Stoltzfus· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMicrobiology

A. Varble

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Author profile →

2 papers

Recent·Most cited

Anti-CRISPR proteins trigger a burst of CRISPR-Cas9 expression that enhances phage defense

R. E. Workman, M. J. Stoltzfus, N. C. Keith, C. W. Euler, J. Bondy-Denomy, J. W. Modell

The paper shows anti-CRISPR proteins in S. pyogenes reduce Cas9 autorepression, leading to increased CRISPR-Cas expression and enhanced phage defense.

bioRxiv · Oct 22, 2023Microbiology

Integration of prophages into CRISPR loci remodels viral immunity in Streptococcus pyogenes

A. Varble, E. Campisi, C. W. Euler, J. Fyodorova, J. Rostol, V. A. Fischetti, L. A. Marraffini

This study shows that the {Phi}AP1.1 phage uses an anti-CRISPR protein to temporarily disable CRISPR immunity, then integrates into the CRISPR locus to modulate immunity through spacer deletion and transfer.

bioRxiv · Oct 9, 2020 · PreprintMicrobiology