Insulin sensitivity is preserved in mice made obese by feeding a high starch diet
A. E. Brandon, L. Small, T.-V. Nguyen, E. Suryana, H. Gong, C. Yassmin, S. E. Hancock, T. Pulpitel, S. Stonehouse, L. Prescott, M. A. Kebede, B. Yau, L.-E. Quek, G. M. Kowalski, C. Bruce, , G. J. Cooney
This study shows that mice fed a high starch diet become obese but remain insulin sensitive, unlike those on a high fat diet, with differences in ceramide levels and lipogenesis contributing to this effect.
bioRxiv · May 25, 2022Physiology