Optogenetic Manipulation of Cell Migration with High Spatiotemporal Resolution Using Lattice Lightsheet Microscopy
W.-C. Tang, Y.-T. Liu, C.-H. Yeh, Y.-L. Lin, Y.-C. Lin, T.-L. Hsu, L. Gao, S.-W. Chang, P. Chen, B.-C. Chen
This study modifies lattice lightsheet microscopy to enable optogenetic manipulation of cell migration with high spatiotemporal resolution, achieving subcellular control and long-term cell viability.
bioRxiv · Jan 2, 2022Cell Biology