Author

G. Kelsoe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 5 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 6 Assay:proteomics· 4 Organism:human· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Organism:rat· 1

Frequent Co-Authors

M. Kuraoka· 5 shared A. Watanabe· 3 shared S. Song· 3 shared A. G. Schmidt· 2 shared G. Bajic· 2 shared K. R. McCarthy· 2 shared L. R. Robinson-McCarthy· 2 shared R. Kotaki· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

5 shared papersImmunology

M. Kuraoka

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

A protective and broadly binding antibody class engages the influenza virus hemagglutinin head at its stem interface

H. C. Simmons, J. Finney, R. Kotaki, Y. Adachi, A. P. Moseman, A. Watanabe, S. Song, L. R. Robinson-McCarthy, V. Le Sage, M. Kuraoka, E. A. Moseman, G. Kelsoe, Y. Takahashi, K. R. McCarthy

This paper identifies a class of human antibodies that bind a conserved HA head-stem interface epitope, offering broad protection against influenza A serotypes in mice.

bioRxiv · Dec 13, 2023Microbiology

An epitope-enriched immunogen increases site targeting in germinal centers

T. M. Caradonna, I. W. Windsor, A. R. Roffler, S. Song, A. Watanabe, G. Kelsoe, M. Kuraoka, A. G. Schmidt

This study shows that an epitope-enriched immunogen preferentially expands RBS-directed antibody responses compared to non-enriched immunogens.

bioRxiv · Dec 1, 2022 · PreprintImmunology

Recall of B cell memory depends on relative locations of prime and boost

M. Kuraoka, C.-H. Yeh, G. Bajic, R. Kotaki, S. Song, S. C. Harrison, G. Kelsoe

The study shows that memory B cells form recall germinal centers more effectively when boosts are given at the same site as the initial immunization, leading to higher mutation levels and avidity in BCRs.

bioRxiv · Dec 17, 2021 · PreprintImmunology

A prevalent focused human antibody response to the influenza hemagglutinin head interface

K. R. McCarthy, J. Lee, A. Watanabe, M. Kuraoka, L. R. Robinson-McCarthy, G. Georgiou, G. Kelsoe, S. Harrison

The paper identifies a focused, protective antibody response targeting a conserved region at the influenza hemagglutinin head interface, showing cross-serotype binding and potential for durable immunity.

bioRxiv · Dec 28, 2020Immunology

Fab-dimerized glycan-reactive antibodies neutralize HIV and are prevalent in humans and rhesus macaques

W. B. Williams, R. Meyerhoff, R. J. Edwards, H. Li, N. Nicely, R. Henderson, Y. Zhou, K. Janowska, K. Mansouri, K. Manne, V. Stalls, A. L. Hsu, M. J. Borgnia, G. Stewart-Jones, M. S. Lee, , B. F. Haynes

The paper identifies Fab-dimerized glycan-reactive antibodies in HIV-infected macaques and HIV-naïve humans that neutralize HIV-1 and can be elicited by vaccination.

bioRxiv · Jun 30, 2020 · PreprintImmunology

Structure-guided molecular grafting of a complex broadly neutralizing viral epitope

G. Bajic, M. J. Maron, M. Tian, G. Kelsoe, M. Kuraoka, A. G. Schmidt

This paper describes the engineering of immunogens that present a conserved viral epitope using avian influenza HAs, showing they are immunogenic and can enrich for RBS-directed antibodies.

bioRxiv · Dec 2, 2019Immunology