Author

R. Kotaki

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

G. Kelsoe· 2 shared M. Kuraoka· 2 shared S. Song· 2 shared Y. Adachi· 2 shared Y. Takahashi· 2 shared A. Nishiyama· 1 shared A. P. Moseman· 1 shared A. Watanabe· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMicrobiology

G. Kelsoe

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A protective and broadly binding antibody class engages the influenza virus hemagglutinin head at its stem interface

H. C. Simmons, J. Finney, R. Kotaki, Y. Adachi, A. P. Moseman, A. Watanabe, S. Song, L. R. Robinson-McCarthy, V. Le Sage, M. Kuraoka, E. A. Moseman, G. Kelsoe, Y. Takahashi, K. R. McCarthy

This paper identifies a class of human antibodies that bind a conserved HA head-stem interface epitope, offering broad protection against influenza A serotypes in mice.

bioRxiv · Dec 13, 2023Microbiology

Two doses of mRNA vaccine elicit cross-neutralizing memory B-cells against SARS-CoV-2 Omicron variant

R. Kotaki, Y. Adachi, S. Moriyama, T. Onodera, S. Fukushi, T. Nagakura, K. Tonouchi, K. Terahara, L. Sun, T. Takano, A. Nishiyama, M. Shinkai, K. Oba, F. Nakamura-Uchiyama, H. Shimizu, , Y. Takahashi

The paper shows that two doses of mRNA vaccine generate cross-neutralizing memory B-cells against SARS-CoV-2 Omicron variant, which are retained and contribute to enhanced antibody responses after a third dose.

bioRxiv · Dec 24, 2021 · PreprintImmunology

Recall of B cell memory depends on relative locations of prime and boost

M. Kuraoka, C.-H. Yeh, G. Bajic, R. Kotaki, S. Song, S. C. Harrison, G. Kelsoe

The study shows that memory B cells form recall germinal centers more effectively when boosts are given at the same site as the initial immunization, leading to higher mutation levels and avidity in BCRs.

bioRxiv · Dec 17, 2021 · PreprintImmunology