Author

C.-R. Lee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 4 Microbiology· 3 Plant Biology· 2 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 7 Research Focus:development & morphogenesis· 5 Organism:Arabidopsis· 4 Research Focus:chromatin & epigenetic regulation· 4 Approach:experimental assay· 4 Organism:E. coli· 3 Assay:proteomics· 3 Assay:whole-genome sequencing· 3

Frequent Co-Authors

C.-Y. Lo· 3 shared S. H. Park· 3 shared U. Choi· 3 shared Y.-P. Lin· 3 shared C.-T. Ting· 2 shared H. B. Lee· 2 shared H.-W. Chen· 2 shared P.-M. Yeh· 2 shared

Activity by Year

2018-2024 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersEvolutionary Biology

C.-Y. Lo

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Author profile →

10 papers

Recent·Most cited

How weedy Arabidopsis thaliana dominated the world: ancestral variation and polygenic adaptation

C.-Y. Lo, C.-C. Chien, Y.-P. Lin, P.-M. Yeh, C.-R. Lee

This study identifies genetic factors underlying demographic turnover in Arabidopsis thaliana, showing polygenic adaptation contributes to the dominance of non-relict populations.

bioRxiv · Apr 28, 2024 · PreprintEvolutionary Biology

Lytic transglycosylase repertoire diversity enables daughter cell separation and antibiotic resistance in Escherichia coli under acidic stress

C.-R. Lee, J. E. Son, S. H. Park, U. Choi

This study identifies MltE and MltC as critical lytic transglycosylases that enable Escherichia coli survival and antibiotic resistance under acidic stress by facilitating daughter cell separation and maintaining membrane integrity.

bioRxiv · Feb 16, 2024 · PreprintMicrobiology

Environment as a limiting factor of the historical global spread of mungbean

P.-W. Ong, Y.-P. Lin, H.-W. Chen, C.-Y. Lo, M. Burlyaeva, T. Noble, R. M. Nair, R. Schafleitner, M. Vishnyakova, E. von Wettberg, M. G. Samsonova, S. Nuzhdin, C.-T. Ting, C.-R. Lee

This study investigates the historical spread of mungbean by analyzing genomes and environmental factors, finding that climatic adaptation, not just human activity, shaped its cultivation range expansion.

eLife · May 19, 2023Peer-reviewedEvolutionary Biology

TWAS coupled with eQTL analysis reveals the genetic connection between gene expression and flowering time in Arabidopsis

P.-S. Chien, P.-H. Chen, C.-R. Lee, T.-J. Chiou

This study combines TWAS and eQTL analysis to identify genetic connections between gene expression and flowering time in Arabidopsis, revealing regulatory modules involving FRI-FLC-SOC1.

bioRxiv · Dec 7, 2022Plant Biology

Ecological and genetic trade-offs drive Arabidopsis thaliana range expansion in Europe

C. C. Bastias, A. Estarague, D. Vile, C.-R. Lee, M. Exposito-Alonso, C. Violle, F. Vasseur

This study shows that ecological trade-offs between dispersal, competition, and stress tolerance shape the geographic distribution of Arabidopsis thaliana in Europe.

bioRxiv · Nov 29, 2022 · PreprintEcology

Distinct selection signatures during domestication and improvement in crops: a tale of two genes in mungbean

Y.-P. Lin, H.-W. Chen, P.-M. Yeh, J. Lin, S. Anand, J. Li, T. Noble, R. M. Nair, R. Schafleitner, M. Samsonova, E. Bishop-von-Wettberg, S. Nuzhdin, C.-T. Ting, R. Lawn, C.-R. Lee

This study compares selection signatures in mungbean domestication and improvement, identifying distinct genomic footprints associated with different genes and selective pressures.

bioRxiv · Sep 8, 2022 · PreprintPlant Biology

Coordinated and distinct LD-transpeptidase-independent roles of peptidoglycan carboxypeptidases DacC and DacA in stress adaptation and cell shape maintenance

U. Choi, S. H. Park, H. B. Lee, C.-R. Lee

This study identifies distinct and coordinated roles of DacC and DacA in stress adaptation and cell shape maintenance in E. coli, independent of LD-transpeptidases and involving interactions with PBPs.

bioRxiv · Sep 6, 2022 · PreprintMicrobiology

Divergent LD-transpeptidase-independent effects of peptidoglycan carboxypeptidases on intrinsic ss-lactam and vancomycin resistance

S. H. Park, U. Choi, S.-H. Ryu, H. B. Lee, J.-W. Lee, C.-R. Lee

This study shows that peptidoglycan carboxypeptidases in E. coli and B. subtilis affect vancomycin and β-lactam resistance independently of LD-transpeptidases, with deletion causing β-lactam sensitivity and vancomycin resistance.

bioRxiv · Apr 4, 2022 · PreprintMicrobiology

The fate of standing variation and new mutation under climate change

C.-Y. Lu, C.-R. Lee

The paper examines how standing genetic variation and new mutations contribute to adaptation under climate change, finding that new mutations are more impactful in novel environments while standing variants are more important in familiar ones.

bioRxiv · Jan 12, 2020 · PreprintEvolutionary Biology

On the post-glacial spread of human commensal Arabidopsis thaliana: journey to the east

C.-W. Hsu, C.-Y. Lo, C.-R. Lee

The paper analyzes genetic variation in Arabidopsis thaliana to trace its post-glacial spread, finding complex demographic patterns and gene flow between non-relict and relict populations in Eurasia.

bioRxiv · Sep 7, 2018Evolutionary Biology