CDDO-Methyl Ester Inhibits BRAF Inhibitor Resistance and Remodels the Myeloid Compartment in BRAF-mutant Melanoma
G. M. Torres, H. C. Jarnagin, C. Park, H. Yang, N. N. Kosarek, R. Bhandari, C.-Y. Wang, F. W. Kolling, M. L. Whitfield, M. J. Turk, K. T. Liby, P. A. Pioli
This study shows that CDDO-Methyl Ester reduces BRAF inhibitor resistance in melanoma by altering the tumor microenvironment and myeloid cell composition.
bioRxiv · Aug 1, 2023 · PreprintImmunology