F. W. Kolling

Coordinated Chemokine Expression Defines Macrophage Subsets Across Tissues

The study identifies seven chemokine-expressing interstitial macrophage subsets in the lung and shows their role in controlling inflammatory cell influx and tertiary lymphoid formation.

Hierarchal single-cell lineage tracing reveals differential fate commitment of CD8 T-cell clones in response to acute infection.

This study uses single-cell lineage tracing to show that CD8 T-cell clones exhibit differential fate commitment during acute infection, with some clones adopting memory or effector biases over time.

Resident memory T cell precursors in tumor draining lymph nodes require type-1 IFN for optimal differentiation

CDDO-Methyl Ester Inhibits BRAF Inhibitor Resistance and Remodels the Myeloid Compartment in BRAF-mutant Melanoma

This study shows that CDDO-Methyl Ester reduces BRAF inhibitor resistance in melanoma by altering the tumor microenvironment and myeloid cell composition.

Pharmacological Induction of mesenchymal-epithelial transition chemosensitizes breast cancer cells and prevents metastatic progression

The paper shows that eribulin induces MET in mesenchymal-like TNBC cells, reducing metastatic potential and increasing sensitivity to other chemotherapeutics.

Characterizing control of memory CD8 T cell differentiation by BTB-ZF transcription factor Zbtb20

This study identifies Zbtb20's role in regulating transcriptional and epigenetic programs during CD8 T cell differentiation and memory formation.

ScRNA-seq Expression of IFI27 and APOC2 Identifies Four Alveolar Macrophage Superclusters in Healthy BALF

The paper identifies four alveolar macrophage superclusters in healthy bronchoalveolar lavage fluid using scRNA-seq and finds they are functionally specialized with conserved frequencies across individuals.