L. Niu

NGAL deficiency elicits Hemophilia-like bleeding and clotting disorder

This study shows NGAL deficiency causes Hemophilia-like bleeding and clotting issues by enhancing coagulation and suppressing antithrombin.

Genomics-Driven Discovery of Myxopyromides, a Class of Polyketidic Amides Associated with Predation of Myxococcus sp. SDU36

The paper identifies myxopyromides, a new class of polyketidic amides produced by Myxococcus sp. SDU36, and links them to predation behavior.

Rapid GPR183-mediated recruitment of eosinophils to the lung after Mycobacterium tuberculosis infection

This study shows that eosinophils migrate to the lungs early after Mycobacterium tuberculosis infection in mice and macaques, mediated by GPR183 and Ch25h, independent of CCR3.

A MYB transcription factor, PlMYB308, plays an essential role in flower senescence of herbaceous peony

This study identifies PlMYB308 as a key regulator of flower senescence in herbaceous peony by modulating hormone levels and anthocyanin biosynthesis.

Cevipabulin-tubulin complex reveals a novel agent binding site on α-tubulin with tubulin degradation effect

The paper identifies a novel binding site on α-tubulin and shows that cevipabulin binding to this site induces tubulin degradation.

A new role of low barrier hydrogen bond in mediating protein stability by small molecules

This study identifies a novel role of low barrier hydrogen bonds in promoting selective tubulin degradation through small molecule interactions.

Comparison of starch granule sizes of maize seeds between parental lines and derived hybrids suggests a maternal inheritance trend

The paper compares starch granule sizes in maize parental lines and hybrids, finding a maternal inheritance trend in seed starch granule size.

Spatially and cell-type resolved quantitative proteomic atlas of healthy human skin

The paper creates a spatially and cell-type resolved proteomic atlas of healthy human skin, quantifying 10,701 proteins across different locations and cell types.

A paired liver biopsy and plasma proteomics study reveals circulating biomarkers for alcohol-related liver disease

This study identifies circulating proteomic biomarkers for alcohol-related liver disease using paired liver biopsy and plasma proteomics, showing improved performance over existing tests.

Structure of the unique tetrameric STENOFOLIA homeodomain bound with DNA

The paper reports the crystal structure of the STENOFOLIA homeodomain bound to DNA, revealing a novel tetrameric binding mechanism and its role in transcriptional repression.

Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Endosomal Sensing by Dendritic Cells in Psoriasis

This study shows that excessive polyamine production in keratinocytes drives self-RNA sensing by dendritic cells, contributing to psoriasis inflammation.

Modified TCA/acetone precipitation of plant proteins for proteomic analysis

The paper describes a modified TCA/acetone precipitation method for plant protein extraction that is faster and reduces protein degradation compared to traditional methods.