Cryo-EM structures of human SID-1 transmembrane family proteins and implications for their low-pH-dependent RNA transport activity
L. Zheng, T. Yang, H. Guo, C. Qi, Y. Lu, H. Xiao, Y. Gao, Y. Liu, Y. Yang, M. Zhou, H. Nguyen, Y. Zhu, F. Sun, C.-Y. Zhang, X. Ji
The paper presents cryo-EM structures of human SIDT1 and SIDT2, revealing their dimeric architecture and demonstrating low-pH-dependent RNA binding and oligomerization.
bioRxiv · Sep 25, 2023Biochemistry