The activation of pentose phosphate pathway flux by hydrogen peroxide is not regulated by NADPH-mediated feedback inhibition
Camila Aburto, Valentina Parada‐Goddard, Alejandro San Martín
This study shows that NADPH levels remain stable under acute H2O2 exposure, contradicting the proposed feedback inhibition mechanism regulating PPP flux.
British Journal of Pharmacology · Nov 16, 2025Peer-reviewedCell Biology