Spatio-temporal X-linked gene reactivation and site-specific retention of epigenetic silencing in the in vivo germline.
Clara Roidor, Laurène Syx, Emmanuelle Beyne, Peggy Raynaud, Dina Zielinski, Aurélie Teissandier, Caroline Lee, Marius Walter, Nicolas Servant, Karim Chébli, Déborah Bourc’his, M. Azim Surani, Maud Borensztein
The paper maps X-linked gene reactivation and epigenetic silencing in developing PGCs, showing partial resistance to reactivation and enrichment of repressive marks.
Nature Structural & Molecular Biology · Jan 21, 2025Peer-reviewedDevelopmental Biology