Author

Cassandra Bui

University of California San Diego

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:mouse· 2 Assay:ATAC-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Eduardo Frías-AnayaiD· 2 shared Helios Gallego-GutiérreziD· 2 shared Jeffrey D. SteinbergiD· 2 shared JoAnn TrejoiD· 2 shared Miguel Alejandro Lopez‐RamireziD· 2 shared Aaryaman Sawhney· 1 shared Andrea Taddei· 1 shared Bethan S. Kilpatrick· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersPathology

Eduardo Frías-AnayaORCID

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2 papers

Recent·Most cited

Integration of artificial intelligence and high-content screening enabled identification of drugs for long-term treatment of cerebral cavernous malformation disease

Eduardo Frías-Anaya, Helios Gallego-Gutiérrez, Cassandra Bui, Janeth O. Birrueta, Jeffrey D. Steinberg, Ingrid R. Niesman, Brendan Gongol, Brina Nguyen, Aaryaman Sawhney, Zaida Mizushima, Nyle Connolly, Bethan S. Kilpatrick, Issam A. Awad, Hemal H. Patel, JoAnn Trejo, , Miguel Alejandro Lopez‐Ramirez

This paper identifies metformin as a potential drug for long-term treatment of cerebral cavernous malformations using AI, high-throughput screening, and animal models.

bioRxiv · Dec 11, 2025 · PreprintPathology

Persistent Activation of Endothelial Cells is Linked to Thrombosis and Inflammation in Cerebral Cavernous Malformation Disease

Helios Gallego-Gutiérrez, Eduardo Frías-Anaya, Cassandra Bui, Louie Zhao, Emily Hsu, Hannah S. Indralingam, Jakob Körbelin, JoAnn Trejo, Jeffrey D. Steinberg, Nathan R. Zemke, Miguel Alejandro Lopez‐Ramirez

This paper identifies JUNB as a key driver of chronic brain vascular inflammation in CCM disease through multi-omic analysis of endothelial cell activation.

bioRxiv · Jun 29, 2025 · PreprintGenomics