Author

Chao-Chieh Lin

Duke UniversityPrimary ORCID profile (0000-0001-5890-9004 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Chao-Chieh LiniD1 paper

Biology Disciplines

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Cancer Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Jen‐Tsan ChiiD· 2 shared Connor D. AmelungiD· 1 shared Denise Dunn· 1 shared Douglas A. MarchukiD· 1 shared Emma Villares· 1 shared Han Kyu LeeiD· 1 shared Jianli Wu· 1 shared Nico Taber· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Jen‐Tsan ChiORCID

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2 papers

Recent·Most cited

Tumor stiffness creates a ferroptotic Achilles heel through YAP SKP2 signaling

Emma Villares, Nico Taber, Shao-Chin Wu, Connor D. Amelung, Jianli Wu, Chao-Chieh Lin, Jen‐Tsan Chi, Sharon Gerecht

This study identifies ferroptosis as a vulnerability in stiff tumors mediated by YAP-SKP2 signaling, showing that stiff tumors are susceptible to ferroptosis induction despite chemotherapy resistance.

bioRxiv · Oct 2, 2026 · PreprintCancer Biology

Targeting the ferroptosis pathway: A novel compound, AZD1390, protects the brain after ischemic stroke

Han Kyu Lee, Chao-Chieh Lin, Denise Dunn, Yubin Chen, Ssu-Yu Chen, Douglas A. Marchuk, Scott Floyd, Jen‐Tsan Chi

This study shows that ATM inhibition with AZD1390 reduces ferroptosis and neuronal death in ischemic stroke models.

bioRxiv · Feb 22, 2025 · PreprintNeuroscience