Author

Charlie Boone

University of Toronto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Genetics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:yeast· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Assay:metabolomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Ankita PriyadarshiniiD· 1 shared Ankita Shivaji Darekar· 1 shared Atindra N. PujariiD· 1 shared Brenda J Andrews· 1 shared Céline SchulziD· 1 shared Chad L. MyersiD· 1 shared Charlotte R. AlthoffiD· 1 shared Dale Climie· 1 shared

Activity by Year

2017-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperGenetics

Ankita PriyadarshiniORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Exploring roles for essential proteins in yeast filamentous growth identifies the WASP homolog Las17 as a regulator of the Cdc42-dependent fMAPK pathway

Atindra N. Pujari, Ankita Priyadarshini, Zhijian Li, Ankita Shivaji Darekar, Deanna Williams, Dale Climie, Sondra Bahr, Helena Friesen, Michelle Li, Joshua M Oken, Robert M Romito, Brenda J Andrews, Charlie Boone, Paul J. Cullen

bioRxiv · Sep 24, 2026 · PreprintGenetics

Dolichol biosynthesis in yeast traces the expanded reaction pathway of higher eukaryotes

Matthew P. Wilson, Takfarinas Kentache, Charlotte R. Althoff, Isabelle Gerin, Shin‐Yi Yu, Marie Morel, Céline Schulz, Sahar Sabry, Jean Jacobs, Julie Graff, Geoffroy de Bettignies, Liliana Surmacz, William C. Sessa, Emile VAN SCHAFTINGEN, Gert Matthijs, , François Foulquier

This study identifies two yeast enzymes, Env9 and Tda5, that perform distinct steps in dolichol biosynthesis, replacing the dual role of DHRSX in humans.

bioRxiv · Apr 24, 2026 · PreprintBiochemistry

Efficient strategies for screening large-scale genetic interaction networks

Raamesh Deshpande, Justin Nelson, Scott W. Simpkins, Michael Costanzo, Jeff S. Piotrowski, Sheena Claire Li, Charlie Boone, Chad L. Myers

The paper introduces COMPRESS-GI, an algorithm that efficiently selects informative genes for genetic interaction screens, enabling large-scale chemical genetic screens with high throughput.

bioRxiv · Jul 5, 2017 · PreprintSystems Biology