Author

Charlotte E L Fisher

Institute of Cancer Research

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Molecular Biology· 1

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Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1

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Ciara Leonard-BookeriD· 1 shared Giulia MazzuccoiD· 1 shared Karim Hussain· 1 shared Max E. DouglasiD· 1 shared Tom D DeeganiD· 1 shared Ylli DoksaniiD· 1 shared

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2026-2026 · peak 1/yr

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1 paper

Recent·Most cited

Molecular BiologyThe EMBO JournalPeer-reviewedJul 9, 2026

Inhibition of lagging strand replication by G-rich telomeric DNA and the shelterin subunit POT1

Ciara Leonard-Booker, Giulia Mazzucco, Charlotte E L Fisher…·Max E. Douglas

This study investigates how telomeres impede replication by showing G-rich DNA and shelterin subunit POT1 block lagging strand replication, with POT1 causing Okazaki fragment skipping and large single-stranded gaps.

1 citation

humanDNA methylation

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