Author

Ciara Leonard-Booker

Institute of Cancer ResearchORCID 0000-0002-7858-1453Unclaimed ORCID profile · follow to get notified of new preprints

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Molecular Biology· 1

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Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Charlotte E L Fisher· 1 shared Giulia MazzuccoiD· 1 shared Karim Hussain· 1 shared Max E. DouglasiD· 1 shared Tom D DeeganiD· 1 shared Ylli DoksaniiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperMolecular Biology

Charlotte E L Fisher

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1 paper

Recent·Most cited

Molecular BiologyThe EMBO JournalPeer-reviewedJul 9, 2026

Inhibition of lagging strand replication by G-rich telomeric DNA and the shelterin subunit POT1

Ciara Leonard-Booker, Giulia Mazzucco, Charlotte E L Fisher…·Max E. Douglas

This study investigates how telomeres impede replication by showing G-rich DNA and shelterin subunit POT1 block lagging strand replication, with POT1 causing Okazaki fragment skipping and large single-stranded gaps.

1 citation

humanDNA methylation

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