Author

Chase M. Hutchins

The University of Texas MD Anderson Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Approach:mechanistic / dynamical model· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Alemayehu Abebe GorfeiD· 2 shared Cynthia V. PagbaiD· 1 shared Geetika Verma· 1 shared Guangwei DuiD· 1 shared Jacob L. JakubeciD· 1 shared Vasanthi JayaramaniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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2 shared papersBiophysics

Alemayehu Abebe GorfeORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintMar 2, 2026

Rheb membrane orientation dynamics and functional consequences elucidated by molecular simulations, single-molecule-FRET and signaling assays

Chase M. Hutchins, Cynthia V. Pagba, Geetika Verma…·Alemayehu Abebe Gorfe

This study uses simulations and assays to show Rheb switches between membrane orientations, affecting mTORC1 activity.

DOI 10.64898/2026.02.27.708535

humanmechanistic / dynamical model

𝕏 PostBluesky

BiophysicsThe Journal of Physical Chemistry BPeer-reviewedJun 28, 2024

Intrinsically disordered membrane anchors of Rheb, RhoA and DiRas3 small GTPases: Molecular dynamics, membrane organization, and interactions

Chase M. Hutchins, Alemayehu Abebe Gorfe

This study uses molecular dynamics simulations to analyze how intrinsically disordered regions of small GTPases interact with membranes, showing that lipid sequence complementarity and electrostatic interactions influence conformational dynamics and lipid sorting.

5 citations

mechanistic / dynamical modelprotein folding & dynamics

𝕏 PostBluesky