Sleep Need, the Key Regulator of Sleep Homeostasis, Is Indicated and Controlled by Phosphorylation of Threonine 221 in Salt Inducible Kinase 3
Yang Li, Chengang Li, Yuxiang Liu, Jianjun Yu, Jingqun Yang, Yunfeng Cui, Tao V. Wang, Chaoyi Li, Lifen Jiang, Meilin Song, Yi Rao
This study identifies SIK3 T221 phosphorylation as an indicator and controller of sleep need, showing reduced sleep need in mutants and after sleep deprivation.
Genetics · Jul 21, 2023Peer-reviewedNeuroscience