Chaoyi Li

This study identifies SNRK as essential for sleep regulation in Drosophila, showing that its loss causes severe sleep loss, which is rescued by neuronal SNRK expression or nicotinic acetylcholine receptor blockade.

This study identifies NALCN and TRPC6 cation channels as mediators of subthreshold inward depolarizing currents in VTA DA neurons and links their down-regulation to depression-like behavior in chronic stress.

This study identifies SIK3 T221 phosphorylation as an indicator and controller of sleep need, showing reduced sleep need in mutants and after sleep deprivation.

This study shows LKB1 is required for sleep in both Drosophila and mice, with reduced sleep observed in Lkb1 mutants across species.