Jianjun Yu

The paper reexamines the sleep phenotype in Camk2a and Camk2b knockout mice, finding sleep reduction in Camk2a but not Camk2b mutants, and both participating in homeostatic sleep rebound.

The paper introduces conditional CCTomics tools to study chemical transmission in Drosophila, demonstrating their effectiveness by analyzing CCT gene expression in clock neurons and revealing an antagonistic relationship between CNMa-CNMaR and PDF-PDFR signaling.

This study identifies SIK3 T221 phosphorylation as an indicator and controller of sleep need, showing reduced sleep need in mutants and after sleep deprivation.

This study identifies calcineurin as a phosphatase that dephosphorylates SIK3 at specific sites, linking it to sleep regulation in mice.