Matrix structure and microenvironment dynamics correlate with chemotherapy response in ovarian cancer
Florian Laforêts, Panoraia Kotantaki, Samar Elorbany, Joseph Hartlebury, Joash Dominic Joy, Beatrice Malacrida, Rachel C Bryan-Ravenscroft, Chiara Berlato, Erica Di Federico, John F. Marshall, Ranjit Manchanda, Wolfgang Jarolimek, Lara Perryman, Eleni Maniati, Frances R. Balkwill
The paper shows that modifying the tumor microenvironment's extracellular matrix improves chemotherapy response in ovarian cancer models.
iScience · Feb 9, 2026Peer-reviewedCancer Biology