Author

Chin-Yen Lin

Broad Institute

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Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Research Focus:protein design· 1

Frequent Co-Authors

Alexander SvanbergssoniD· 1 shared Benjamin E. DevermaniD· 1 shared Daniel A. SpragueiD· 1 shared Eric Vallabh MinikeliD· 1 shared Fiona E. SerackiD· 1 shared Jencilin Johnston· 1 shared Jessie R. DavisiD· 1 shared John W. HarveyiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Alexander SvanbergssonORCID

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1 paper

Recent·Most cited

BI-TfR1 CapX rapidly transits the blood-brain barrier for efficient, low-dose gene delivery throughout the CNS

Ken Y. Chan, Chin-Yen Lin, Qin Huang, Simon Pacouret, Qingxia Zheng, John W. Harvey, Pamela P. Brauer, Jencilin Johnston, Fiona E. Serack, Jessie R. Davis, Nikita G Kamath, Saša Jereb, Daniel A. Sprague, Alexander Svanbergsson, Magalie Boucher, , Benjamin E. Deverman

The paper describes BI-TfR1 CapX, a gene delivery vector that efficiently crosses the blood-brain barrier, transduces CNS neurons and astrocytes, and reduces Prnp mRNA with low doses.

bioRxiv · Sep 29, 2026 · PreprintNeuroscience