Author

Christiane Wirbelauer

Friedrich Miescher Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Assay:ATAC-seq· 2 Assay:ChIP-seq· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Dirk SchübeleriD· 3 shared Lukas BurgeriD· 3 shared Murat IskariD· 3 shared Leslie Hoerner· 2 shared Sevi DurduiD· 2 shared Daniel HeßiD· 1 shared Francesca MasoniiD· 1 shared Fumiya Moribe· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersMolecular Biology

Dirk SchübelerORCID

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3 papers

Recent·Most cited

Modular control of CpG islands by chromatin-opening transcription factors specifies transcription start sites

Fumiya Moribe, Murat Iskar, Sevi Durdu, Christiane Wirbelauer, Leslie Hoerner, Sebastien Smallwood, Lukas Burger, Dirk Schübeler

The paper shows chromatin-opening transcription factors determine transcription start sites by binding near the initiation site, with loss of these factors redirecting initiation to secondary sites.

bioRxiv · May 6, 2026 · PreprintMolecular Biology

Chromatin-dependent motif syntax defines differentiation trajectories

Sevi Durdu, Murat Iskar, Luke Isbel, Leslie Hoerner, Christiane Wirbelauer, Lukas Burger, Daniel Heß, Vytautas Iešmantavičius, Dirk Schübeler

The paper identifies chromatin-dependent motif syntax that distinguishes binding patterns of NGN2 and MyoD1 during differentiation, revealing how context-specific chromatin states influence transcription factor specificity.

Molecular Cell · Aug 1, 2025Peer-reviewedGenomics

Systematic assessment of ISWI subunits reveals that NURF creates local accessibility for proper CTCF function

Mario Iurlaro, Francesca Masoni, Christiane Wirbelauer, Murat Iskar, Lukas Burger, Dirk Schübeler

The paper shows that NURF subunit BPTF is critical for chromatin accessibility and CTCF function, affecting cohesin positioning and insulation.

bioRxiv · Jul 25, 2023 · PreprintMolecular Biology