Lukas Burger

The paper shows chromatin-opening transcription factors determine transcription start sites by binding near the initiation site, with loss of these factors redirecting initiation to secondary sites.

This paper introduces a deep learning framework to quantify chromatin sensitivity of transcription factors, revealing a continuum of sensitivity rather than distinct hierarchical or cooperative mechanisms.

The paper identifies chromatin-dependent motif syntax that distinguishes binding patterns of NGN2 and MyoD1 during differentiation, revealing how context-specific chromatin states influence transcription factor specificity.

The paper shows that NURF subunit BPTF is critical for chromatin accessibility and CTCF function, affecting cohesin positioning and insulation.

This study shows that Trim24 restricts p53's ability to open chromatin by binding to closed chromatin regions and interacting with unmethylated histone H3 lysine 4.

monaLisa identifies transcription factors from experimental data by integrating with Bioconductor packages for motif analysis.