Timed chromatin invasion during mitosis governs prototype foamy virus integration site selection and infectivity
Floriane Lagadec, Parmit Kumar Singh, Christina Calmels, Delphine Lapaillerie, Dirk Lindemann, Vincent Parissi, Peter Cherepanov, Alan Engelman, Paul Lesbats
This study shows that PFV Gag protein interacts with mitotic chromatin, and altered binding affects integration site selection and infectivity.
Nucleic Acids Research · May 16, 2025Peer-reviewedMicrobiology