Delphine Lapaillerie

This study investigates how chromatin compaction affects retroviral integration by analyzing the interaction between intasomes and nucleosomes, revealing distinct strategies in HIV-1 and PFV.

This study shows that PFV Gag protein interacts with mitotic chromatin, and altered binding affects integration site selection and infectivity.

The paper shows toxin-antitoxin systems regulate cassette recombination dynamics in chromosomal integrons by killing cells when excision rates are too high.

The paper demonstrates that integron integrase can insert cassettes outside classical att sites, leading to new recombination sites called attG and expanding integron roles in bacterial evolution.

The paper investigates cassette recruitment in the chromosomal integron of Vibrio cholerae during conjugation and natural transformation, showing that horizontally transferred cassettes can be inserted and expressed.