Author

Paul Lesbats

Centre National de la Recherche ScientifiqueORCID 0000-0002-4623-0675Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Assay:Hi-C· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Delphine LapaillerieiD· 2 shared Vincent ParissiiD· 2 shared Alan EngelmaniD· 1 shared Camille TumiottoiD· 1 shared Carole Bertinetti· 1 shared Christina Calmels· 1 shared Dirk LindemanniD· 1 shared F.G. MartinsiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMicrobiology

Delphine LapaillerieORCID

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Author profile →

2 papers

Recent·Most cited

Molecular basis for the regulation of retroviral nucleosomal integration by chromatin compaction

Delphine Lapaillerie, Yury Zgadzay, F.G. Martins, Carole Bertinetti, Michel Autin, Julien Batisse, Camille Tumiotto, Paul Lesbats, Marc Ruff, Sérgio Filipe Sousa, Vincent Parissi

This study investigates how chromatin compaction affects retroviral integration by analyzing the interaction between intasomes and nucleosomes, revealing distinct strategies in HIV-1 and PFV.

Nucleic Acids Research · Jul 3, 2026Peer-reviewedMicrobiology

Timed chromatin invasion during mitosis governs prototype foamy virus integration site selection and infectivity

Floriane Lagadec, Parmit Kumar Singh, Christina Calmels, Delphine Lapaillerie, Dirk Lindemann, Vincent Parissi, Peter Cherepanov, Alan Engelman, Paul Lesbats

This study shows that PFV Gag protein interacts with mitotic chromatin, and altered binding affects integration site selection and infectivity.

Nucleic Acids Research · May 16, 2025Peer-reviewedMicrobiology