Author

Christophe Lemetre

Rockefeller University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:DNA methylation· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Zhengdong Zhang· 2 shared Aaron GoldeniD· 1 shared Adam AutoniD· 1 shared Adrián Morales-AmadoriD· 1 shared Batya Gounder· 1 shared Brett S. Abrahams· 1 shared Cathal SeoigheiD· 1 shared Christine M. Alaimo· 1 shared

Activity by Year

2014-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersGenomics

Zhengdong Zhang

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3 papers

Recent·Most cited

Oxydifficidin, a potent Neisseria gonorrhoeae antibiotic due to DedA assisted uptake and ribosomal protein RplL sensitivity

Jingbo Kan, Adrián Morales-Amador, Yozen A. Hernandez, Melinda A. Ternei, Christophe Lemetre, Logan W Maclntyre, Nicolas Biais, Sean F. Brady

This study identifies oxydifficidin as a potent antibiotic against Neisseria gonorrhoeae, effective against drug-resistant strains, due to DedA-mediated uptake and sensitivity to ribosomal protein RplL.

eLife · Aug 1, 2024Peer-reviewedMicrobiology

RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships

Julie Nadel, Rodoniki Athanasiadou, Christophe Lemetre, Neil Ari Wijetunga, Pilib Ó Broin, Hanae Sato, Zhengdong Zhang, Jeffrey Jeddeloh, Cristina Montagna, Aaron Golden, Cathal Seoighe, John M. Greally

The paper identifies RNA:DNA hybrids in the human genome, showing they are purine-rich, associated with hypomethylation and heterochromatin domains, and bound by ILF2/ILF3 transcription factors.

Epigenetics & Chromatin · Nov 16, 2015Peer-reviewedGenomics

MOSAIC EPIGENETIC DYSREGULATION OF ECTODERMAL CELLS IN AUTISM SPECTRUM DISORDER

Esther R. Berko, Masako Suzuki, Faygel Beren, Christophe Lemetre, Christine M. Alaimo, R. Brent Calder, Karen Ballaban-Gil, Batya Gounder, Kaylee Kampf, Jill Kirschen, Shahina B. Maqbool, Zeineen Momin, David M. Reynolds, Natalie Russo, Lisa Shulman, , John Greally

This study identifies epigenetic dysregulation in ectodermal cells of individuals with ASD born to older mothers, suggesting a potential role for epigenetic changes in ASD pathogenesis.

bioRxiv · May 6, 2014Genomics