Author

Christopher Dunsby

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

A. J. Narvaez· 1 shared A. M. I. Le MaroisiD· 1 shared Charles SwantoniD· 1 shared Deborah Caswell· 1 shared Erik SahaiiD· 1 shared Fabian Frӧhlich· 1 shared Hugh SparksiD· 1 shared Julian DownwardiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. J. Narvaez

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1 paper

Recent·Most cited

Imaging of MAP kinase dynamics reveals endocytic regulation of pulsatile signalling and network re-wiring in response to targeted therapy in EGFR-mutant non-small cell lung cancer

A. M. I. Le Marois, Sasha Bailey, Steven Hooper, Sunil Kumar, Hugh Sparks, Yuriy Alexandrov, Deborah Caswell, Fabian Frӧhlich, Karin Schlegelmilch, Karishma Valand, Matthew Martin, A. J. Narvaez, Charles Swanton, Julian Downward, Christopher Dunsby, , Erik Sahai

The paper uses single-cell imaging to show that drug-tolerant cells in EGFR-mutant lung cancer rewired ERK signaling through endocytic pathways and adhesion complexes, driven by YAP and PTPRS.

bioRxiv · May 14, 2024 · PreprintCancer Biology