Author

Christopher McDermott-Roe

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Aavash Baral· 1 shared Aino Paasinen-Sohns· 1 shared Andrej BenjakiD· 1 shared Bastian DislichiD· 1 shared Carmen CardozoiD· 1 shared Carmen PerryiD· 1 shared Clelia PistoniiD· 1 shared David E. RootiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Aavash Baral

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1 paper

Recent·Most cited

Aurora kinase A is a synthetic lethal target in FANCA-deficient cancers

Dilara Akhoundova, Martín González Fernández, Aavash Baral, Andrej Benjak, Carmen Perry, Dinda Shezaria Hardy Lubis, Ladina Hörtensteiner, Saskia Hussung, Lea Lingg, Sina Maletti, Aino Paasinen-Sohns, Marika Lehner, Bastian Dislich, Erik Vassella, Simone de Brot, , Mark A. Rubin

The paper identifies Aurora kinase A as a synthetic lethal target in FANCA-deficient cancers and shows AURKA inhibition induces chromosomal instability and G2/M arrest in these cells.

npj Precision Oncology · Jul 11, 2026Peer-reviewedCancer Biology