Author

Erik Vassella

University of BernORCID 0000-0001-7982-8713Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Dilara AkhoundovaiD· 2 shared Lea LinggiD· 2 shared Martín González FernándeziD· 2 shared Paola FrancicaiD· 2 shared Saskia HussungiD· 2 shared Simone de BrotiD· 2 shared Sven RottenbergiD· 2 shared Aavash Baral· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Dilara AkhoundovaORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer Biologynpj Precision OncologyPeer-reviewedJul 11, 2026

Aurora kinase A is a synthetic lethal target in FANCA-deficient cancers

Dilara Akhoundova, Martín González Fernández, Aavash Baral…·Mark A. Rubin

The paper identifies Aurora kinase A as a synthetic lethal target in FANCA-deficient cancers and shows AURKA inhibition induces chromosomal instability and G2/M arrest in these cells.

DOI 10.1038/s41698-026-01596-7

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintOct 14, 2025

TAOK1 regulates chemo- and radiosensitivity in BRCA1/2-deficient tumors

Lea Lingg, Merve Mutlu, Arunasalam Naguleswaran…·Paola Francica

This study identifies TAOK1 as a regulator of replication fork stability in BRCA1/2-deficient tumors, showing it enhances sensitivity to PARPi and IR through PCNA and ISG15 interactions.

DOI 10.1101/2025.10.14.682031

humanexperimental assay

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Cancer BiologyBiology Methods and ProtocolsPeer-reviewedJan 1, 2024

Methods in cancer research: Assessing therapy response of spheroid cultures by life cell imaging using a Cost-Effective Live-Dead Staining Protocol

Jaison Phour, Erik Vassella

The paper develops a cost-effective live-dead staining protocol for monitoring therapy response in spheroid cultures over 10 days using calcein-AM and Helix NP Blue.

11 citations

humanimaging

𝕏 PostBluesky