U2AF1 S34F enhances tumorigenic potential of lung cells by exhibiting synergy with KRAS mutation and altering response to environmental stress
Cindy E Liang, Eva Hrabeta‐Robinson, Selam Mehreteab, Amit K. Behera, Colette Felton, Isobel J. Fetter, Cameron M. Soulette, Alexis M. Thornton, Shaheen S. Sikandar, Angela Norie Brooks
This study shows U2AF1S34F enhances lung cell tumorigenicity when combined with KRAS mutations and environmental stress, altering splicing and stress responses.
bioRxiv · Sep 11, 2024 · PreprintCancer Biology