Author

Julie Necarsulmer

National Institute on Drug AbuseORCID 0000-0002-0669-2023Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1 Organism:rat· 1 Organism:zebrafish· 1

Frequent Co-Authors

Adriana S. BeltrániD· 1 shared Amy Phan· 1 shared Antonio PlanchartiD· 1 shared Audra F. BryaniD· 1 shared Austin J. HepperlaiD· 1 shared Baggio EvangelistaiD· 1 shared Brandon K. HarveyiD· 1 shared Braxton D. GreeriD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperNeuroscience

Adriana S. BeltránORCID

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2 papers

Recent·Most cited

High-Content Screening Identifies Dithiocarbamates As A Class Of Chemicals That Disrupts TDP-43 Proteostasis

Giulia Fragola, Ryan D. Weeks, Justin Wolter, Audra F. Bryan, Katheryn Natalya Kapfer, Xu Tian, Julie Necarsulmer, Baggio Evangelista, Vanya Bhat, Omeed K Arooji, Adriana S. Beltrán, Tara A. Brennan, Matthew J. Niederhuber, Austin J. Hepperla, Leonard B. Collins, , Todd J Cohen

This study identifies dithiocarbamates as chemicals that disrupt TDP-43 proteostasis by causing aggregation and loss of function through redox imbalance and zinc homeostasis disruption.

bioRxiv · Aug 22, 2026 · PreprintNeuroscience

Generation and characterization of a tamoxifen-inducible, Cre driver rat for transgene expression in microglia

Elliot J. Glotfelty, Lamarque M. Coke, Evan E. Hart, Cole Rivell, Amy Phan, Braxton D. Greer, Reinis Svarcbahs, Elizabeth Fielding, Julie Necarsulmer, Lowella V. Fortuno, Francois Vautier, Patricia J. Gearhart, Geoffrey M. Schoenbaum, Christopher T. Richie, Brandon K. Harvey

The paper describes the generation of a tamoxifen-inducible Cre driver rat for microglial transgene expression and validates its specificity and functionality.

Scientific Reports · Dec 9, 2025Peer-reviewedNeuroscience