Author

Colleen Mcloughlin

NYU Langone Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Assay:ChIP-seq· 1 Assay:CRISPR screen· 1 Research Focus:database / resource· 1 Assay:DNA methylation· 1 Research Focus:fine-mapping· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Jef D. BoekeiD· 2 shared Matthew T. MauranoiD· 2 shared Ran BroshiD· 2 shared André Mauricio Ribeiro-dos-SantosiD· 1 shared Arushi VarshneyiD· 1 shared Brendan R. CamellatoiD· 1 shared Daniel J PaulliD· 1 shared David FenyöiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersGenetics

Jef D. BoekeORCID

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2 papers

Recent·Most cited

Genome writing and Targeted Delivery of the NKX6-3/ANK1 gene cluster and its Type 2 Diabetes GWAS Variants to Human iPSCs

Noor Chalhoub, Arushi Varshney, Weimin Zhang, Skyler A. Uhl, Jon M. Laurent, Colleen Mcloughlin, Hannah Ashe, Xingrui Mou, Nathan Dale, Kiran Ramnarine, Daniel J Paull, Jordan Goldberg, Matthew T. Maurano, Ran Brosh, David Fenyö, , Jef D. Boeke

This paper introduces a method to deliver synthetic haplotypes containing T2D GWAS variants to hiPSCs to study their functional impact on differentiation.

bioRxiv · Jan 5, 2026 · PreprintGenetics

Synthetic genomic dissection of enhancer context sensitivity and synergy

Raquel Ordóñez, André Mauricio Ribeiro-dos-Santos, Colleen Mcloughlin, Gwen Ellis, Hannah J. Ashe, Nerea Berastegui, Ran Brosh, Miłosz Majewski, Kelly Barriball, Brendan R. Camellato, Jef D. Boeke, Matthew T. Maurano

The paper identifies context-dependent enhancer synergy in mouse embryonic stem cells, showing that enhancers can significantly boost neighboring DHS activity and that this synergy depends on distance and specific transcription factor sequences.

bioRxiv · Aug 13, 2025 · PreprintGenomics