Mutation of Vsx genes in zebrafish highlights the robustness of the retinal specification network.
Joaquín Letelier, Lorena Buono, María Almuedo‐Castillo, Jingjing Zang, Constanza Mounieres, Sergio González‐Díaz, Rocío Polvillo, Estefanía Sanabria‐Reinoso, Jorge Corbacho, Ana Sousa‐Ortega, Ruth Díez del Corral, Stephan C. F. Neuhauss, Juan Ramón Martínez‐Morales
The paper shows that vsx gene mutation in zebrafish causes bipolar cell depletion and visual impairment but maintains neural retina specification, highlighting genetic redundancy and network robustness.
eLife · Apr 14, 2023Peer-reviewedDevelopmental Biology