Jingjing Zang

Magnetoelectric Microrobots for Spinal Cord Injury Regeneration

This paper introduces NPCbots, magnetoelectric microrobots for spinal cord injury repair, showing improved neural regeneration and behavior in zebrafish models.

CLN5 deficiency impairs glucose uptake in Batten disease

This study develops a zebrafish model of CLN5 deficiency, revealing impaired glucose metabolism as a novel feature of NCL.

Defects in exosome biogenesis are associated with sensorimotor defects in zebrafish vps4a mutants

This paper identifies a zebrafish vps4a mutation causing sensorimotor defects by reducing Vps4a ATPase activity and exosome biogenesis, affecting specific reflexes and vision.

Glutamate Transporters are Involved in Direct Inhibitory Synaptic Transmission in the Vertebrate Retina

The paper shows that glutamate transporters in ON-bipolar cells modulate inhibitory synaptic transmission in the vertebrate retina by affecting response kinetics and amplitude.

Mutation of Vsx genes in zebrafish highlights the robustness of the retinal specification network.

The paper shows that vsx gene mutation in zebrafish causes bipolar cell depletion and visual impairment but maintains neural retina specification, highlighting genetic redundancy and network robustness.

Specialization of the photoreceptor transcriptome by Srrm3-dependent microexons is required for outer segment maintenance and vision

The paper identifies Srrm3-dependent microexons as critical for photoreceptor function and vision, showing their role in outer segment maintenance and their loss leading to blindness.

The Bardet-Biedl protein Bbs1 controls photoreceptor outer segment protein and lipid composition

This study shows that Bbs1 is essential for maintaining photoreceptor outer segment lipid composition and function, with loss leading to early visual deficits and retinal degeneration.

Circadian Regulation of Vertebrate Cone Photoreceptor Function

The paper examines circadian regulation of visual transduction regulators in zebrafish and mice, finding rhythmic gene expression and physiological responses aligned with their diurnal/nocturnal activity patterns.

Antisense oligonucleotide-based treatment of retinitis pigmentosa caused by USH2A exon 13 mutations

This study demonstrates that QR-421a induces exon 13 skipping in USH2A transcripts, restoring retinal function in zebrafish and non-human primates.