Stephan C. F. Neuhauss

This study uses live imaging in zebrafish to show that hindbrain medulloblastoma cells spread more frequently than forebrain or midbrain tumors and that dasatinib reduces dissemination.

This study shows that famlasertib, a MAP4K inhibitor, reduces medulloblastoma cell invasion in vitro and in zebrafish models without causing developmental toxicity.

This paper introduces NPCbots, magnetoelectric microrobots for spinal cord injury repair, showing improved neural regeneration and behavior in zebrafish models.

The paper shows that On-Off coding in vertebrate vision is a latent, dynamically regulated computation rather than a fixed circuit feature, revealed through zebrafish and mouse studies.

The paper introduces a zebrafish biosensor for detecting kidney tubule dysfunction and uses it to study metal toxicity and drug screening.

The paper shows that EAAT5b and EAAT7 have wavelength-specific roles in zebrafish retinal function, affecting responses to short and long-wavelength stimuli but not middle-wavelengths.

This study investigates galanin's role in regulating whole-brain activity and stress responses in larval zebrafish using Ca2+ imaging and genetic/pharmacological manipulations.

This study develops a zebrafish model of CLN5 deficiency, revealing impaired glucose metabolism as a novel feature of NCL.

This paper identifies a zebrafish vps4a mutation causing sensorimotor defects by reducing Vps4a ATPase activity and exosome biogenesis, affecting specific reflexes and vision.

This study shows that group III mGluR-mediated inhibition in the habenula regulates sensory processing and defensive behaviors in zebrafish and mice.

The paper shows that glutamate transporters in ON-bipolar cells modulate inhibitory synaptic transmission in the vertebrate retina by affecting response kinetics and amplitude.

The paper shows that vsx gene mutation in zebrafish causes bipolar cell depletion and visual impairment but maintains neural retina specification, highlighting genetic redundancy and network robustness.

The paper introduces a novel Schmidt objective for high-resolution imaging in cleared tissues, achieving high NA, long WD, and large FOV with only two optical elements.

The paper compares zebrafish epilepsy models to identify conserved and divergent features of neural and behavioral activity, finding that photic stimulation reliably evokes seizures with a characteristic depressed state.

The paper identifies Srrm3-dependent microexons as critical for photoreceptor function and vision, showing their role in outer segment maintenance and their loss leading to blindness.

The paper identifies manganese deficiency and neurotoxicity in zebrafish slc39a14 mutants through transcriptome analysis, revealing key molecular pathways involved in manganese homeostasis disruption.

This study shows that Bbs1 is essential for maintaining photoreceptor outer segment lipid composition and function, with loss leading to early visual deficits and retinal degeneration.

FRaeppli enables multispectral imaging for cell tracing and tissue analysis in zebrafish, revealing new canalicular topologies in hepatocytes.

This study shows that loss of eaat2a in zebrafish causes seizures and reduced neuronal activity due to glutamate imbalance.

This study shows that loss of rlbp1a in zebrafish causes cone dysfunction, lipid deposits, and photoreceptor degeneration, mimicking human retinal diseases caused by RLBP1 mutations.

The paper examines circadian regulation of visual transduction regulators in zebrafish and mice, finding rhythmic gene expression and physiological responses aligned with their diurnal/nocturnal activity patterns.

This study demonstrates that QR-421a induces exon 13 skipping in USH2A transcripts, restoring retinal function in zebrafish and non-human primates.

This study identifies a JBTS-associated protein module involving ARMC9 and TOGARAM1 that regulates ciliary stability and post-translational modifications.

This study shows that Nup133 deficiency in zebrafish causes kidney cysts and glomerular damage, mimicking human nephrotic syndrome features.

The paper investigates PKCα and PKCβ expression in zebrafish retina, finding that antibodies label multiple bipolar cell subtypes rather than specific ones.