Author

Crescenzo Frascogna

Italian Institute of Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

Aki MannineniD· 1 shared Aleksander Jarmakowicz· 1 shared Alessandro Avallone· 1 shared Amrinder S. NainiD· 1 shared Anette SchmidtiD· 1 shared Anne Ahtikoski· 1 shared Atharva AgasheiD· 1 shared Bruno Sainz· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Aki ManninenORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

β4-integrins safeguard nuclear mechanics to suppress prostate cancer progression

Anette Schmidt, Rong Wei, Paulina Nastały, Maliha Mehnaz-Enamul, Atharva Agashe, Michał Rychłowski, Katarzyna Bury, Saara Koivusalo, Qin Zhang, Crescenzo Frascogna, Carlo F. Natale, Xiayun Yang, Aleksander Jarmakowicz, Anne Ahtikoski, Markku H. Vaarala, , Aki Manninen

This study identifies β4-integrins as critical for maintaining nuclear mechanics and integrity in prostate cancer, linking cell-ECM adhesion to genome stability and patient survival.

bioRxiv · Sep 2, 2026 · PreprintCancer Biology

Mechanobiology-guided drug repurposing identifies budesonide as an inhibitor of stiffness-induced PDAC aggressiveness

Simone Mas, Marco Cristiano, Eduardo Ibello, Alessandro Avallone, Crescenzo Frascogna, Bruno Sainz, Enza Lonardo, Lucia Altucci, Gilda Cobellis, Eduardo Jorge Patriarca, Paolo A. Netti, Gabriella Minchiotti, Valeria Panzetta, Cristina D’Aniello

This study identifies budesonide as a drug that inhibits stiffness-induced aggressiveness in pancreatic ductal adenocarcinoma by targeting mechanical cues.

bioRxiv · Jul 20, 2026 · PreprintBioengineering