Author

Eduardo Jorge Patriarca

Institute of Genetics and BiophysicsORCID 0000-0002-6301-7534Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Gabriella MinchiottiiD· 3 shared Cristina D’AnielloiD· 2 shared Alessandro Avallone· 1 shared Alessandro FiorenzanoiD· 1 shared Alfonso Martínez-Arias· 1 shared Annalisa FicoiD· 1 shared Arianna Coppola· 1 shared Bruno Sainz· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersDevelopmental Biology

Gabriella MinchiottiORCID

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3 papers

Recent·Most cited

Mechanobiology-guided drug repurposing identifies budesonide as an inhibitor of stiffness-induced PDAC aggressiveness

Simone Mas, Marco Cristiano, Eduardo Ibello, Alessandro Avallone, Crescenzo Frascogna, Bruno Sainz, Enza Lonardo, Lucia Altucci, Gilda Cobellis, Eduardo Jorge Patriarca, Paolo A. Netti, Gabriella Minchiotti, Valeria Panzetta, Cristina D’Aniello

This study identifies budesonide as a drug that inhibits stiffness-induced aggressiveness in pancreatic ductal adenocarcinoma by targeting mechanical cues.

bioRxiv · Jul 20, 2026 · PreprintBioengineering

Non-cell-autonomous control of gastruloid development by the lncRNA T-UCstem1 through DKK1-dependent modulation of WNT signalling

Arianna Coppola, Filomena Amoroso, Federica Saracino, Gennaro Andolfi, Edoardo Sozzi, Paolo Salerno, Pietro Zoppoli, Alessandro Fiorenzano, Giuseppe Merla, Eduardo Jorge Patriarca, Gabriella Minchiotti, Annalisa Fico

This study identifies T-UCstem1 as a key lncRNA regulating gastruloid development through DKK1-dependent modulation of WNT signaling, affecting anteroposterior axis extension and cellular identity.

bioRxiv · Sep 18, 2024 · PreprintDevelopmental Biology

Gastruloid development competence discriminates different states of pluripotency between naïve and primed

Federica Cermola, Cristina D’Aniello, Rosarita Tatè, Dario De Cesare, Alfonso Martínez-Arias, Gabriella Minchiotti, Eduardo Jorge Patriarca

The paper introduces a GFE assay to measure gastruloid formation efficiency, showing that it discriminates between naive and primed pluripotency states in mouse ESCs.

Stem Cell Reports · Jan 21, 2021Peer-reviewedDevelopmental Biology